Can driving cause high blood pressure? Driving can contribute to developing or worsening hypertension (high blood pressure). Prolonged periods of sitting, lack of physical activity, and poor eating habits are common among truckers who may eat on the go while driving. However, it is possible to manage this condition through lifestyle changes such as exercising regularly, maintaining a balanced diet, reducing stress, getting adequate sleep, limiting alcohol consumption, smoking cessation, and regular check-ups with your doctor. What blood pressure is too high for driving? Blood pressure must be below 180/100 mmHg.