The ONE organ responsible for high blood pressure.
High Blood Pressure May Accelerate Osteoporosis, Bone Aging
Can osteoporosis cause high blood pressure?
Researchers reported that women with osteoporosis had a higher prevalence of high blood pressure. The researchers concluded that “Hypertension was significantly associated with osteoporosis.” A study completed in 2020 reported that bone marrow is affected by hypertension.
How does high blood pressure affect the bones?
High blood pressure can result in bone loss or osteoporosis. It causes a greater amount of calcium than normal to be lost through urine excretion which reduces bone mass. This weakens the bones and increases the risk of fractures.
- 12 young mice with induced high blood pressure
- 11 older mice with induced high blood pressure
- 13 young mice without induced high blood pressure
- 9 older mice without high blood pressure
- A 24% reduction in bone volume
- An 18% reduction in thickness of the sponge-like trabecular bone at the end of long bones, such as femurs or the spinal column
- A 34% reduction in the estimated ability of bones to withstand different types of force, called failure force, which can lead to weaker bones and fractures later in life
What is osteoporosis?Osteoporosis is the leading cause of fractures in postmenopausal women and older men. Many people do not know they have it until they break a bone, receiving a diagnosis after a routine screening. Fractures most often occur in the hip, vertebrae, spine, or wrist but can occur in any bone. Osteoporosis can occur at any age, but your risk increases as you age. It is most common in non-Hispanic white women, Asian women, and non-Hispanic white men.
The impact of high blood pressureThere are numerous reasons why high blood pressure impacts osteoporosis. “High blood pressure may be more likely to alter the blood supply to the bone and bone marrow, which can possibly stimulate inflammatory mediators,” Dr. Ragavendra Baliga, a specialist in cardiovascular disease and advanced heart failure at The Ohio State University Wexner Medical Center, told Healthline. “The theory is that younger mice have a low inflammatory burden. When increasing their angiotensin II level, we make them hypertensive. There is evidence that hypertension is a pro-inflammatory state,” Dr. Rigved Tadwalkar, a cardiologist at Providence Saint John’s Health Center in California, told Healthline. “Since the young mice were not exposed to significant inflammation prior, the acute inflammatory load might be overwhelming to the bone, leading to processes that favor bone loss.” Previous studies back up the idea that high blood pressure is related to osteoporosis. A 2021 study from China involved 2,039 postmenopausal women. There were 678 women with osteoporosis and 1,361 without the condition. Researchers reported that women with osteoporosis had a higher prevalence of high blood pressure. The researchers concluded that “Hypertension was significantly associated with osteoporosis.” A study completed in 2020 reported that bone marrow is affected by hypertension. The scientists noted clinical evidence of an association between hypertension and osteoporosis. A meta-analysis of 17 articles conducted in 2017, which included almost 40,000 people, found that high blood pressure can reduce bone mineral density in some areas of the body. “Previous studies have also found that medications to reduce [high blood pressure} reduce fractures,” said Baliga.
Ways to reduce osteoporosis riskWhile many people do not know they have osteoporosis, there are steps you can take to reduce your risk, according to the National Institutes of Health. They include:
- Staying physically active
- Regularly participating in weight-bearing exercises, such as walking
- Drinking alcohol in moderation
- Not smoking
- Eating a well-balanced diet rich in calcium and vitamin D
- Take medications prescribed for osteoporosis if your doctor believes they are necessary