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How Do Blood Pressure Medications Work? Updated 2022
Blood pressure medicines can keep blood pressure at a healthy level by1: Causing your body to get rid of water, which decreases the amount of water and salt in your body to a healthy level. Relaxing your blood vessels. Making your heart beat with less force.
Medication helps lower blood pressure quickly, typically within a few days. However, it may not be the best long-term treatment due to side effects. Medication can help manage high blood pressure while a person changes their underlying lifestyle that may be causing high blood pressure.
Understanding Blood Pressure Numbers
Blood pressure is determined by two things – the amount and force of blood your heart pumps (the faster your heart rate, the more blood that is pumped) and the amount of resistance to that blood as it flows through your arteries. The more blood your heart pumps and the narrower your arteries, the higher your blood pressure will be. A blood pressure reading consists of two numbers:- Systolic: The first, or top, number measures the pressure in your arteries when your heart beats.
- Diastolic: The second, or bottom, number measures the pressure in your arteries when your heart rests between beats.
- Less than 120/80 = Normal
- 120-129/80 = Elevated blood pressure
- 130-139/80-89 = Stage 1 hypertension
- 140/90 or higher = Stage 2 hypertension
- 180/120 or higher = Hypertensive crisis
Lifestyle Modifications to Reduce Blood Pressure
Elevated blood pressure and Stage 1 hypertension can sometimes be managed with lifestyle modifications only. These may include:- Eat a heart healthy, low-sodium, low-fat diet
- Get moderate exercise (consult your doctor before beginning any exercise program)
- Quit smoking
- Reduce or eliminate alcohol and caffeine
- Lose weight
Medications for High Blood Pressure
There are many medications to treat hypertension that work in different ways to lower blood pressure. Listed below are the most common types/classes of medications prescribed along with a general explanation of how they work. Thiazide Diuretics Diuretics help the body get rid of excess sodium (salt) and water to help control blood pressure. Thiazide diuretics act directly on the kidneys to promote fluid removal through urination. They are often used in combination with other antihypertensive medications. (Note: Over-the-counter diuretics, often sold as “water pills” are not regulated and, therefore, not recommended.) ACE Inhibitors ACE stands for angiotensin-converting enzyme. Angiotensin is a chemical that causes the arteries to become narrow throughout the body, especially in the kidneys. ACE inhibitors help the body produce less angiotensin, which helps the blood vessels relax and open up, which, in turn, lowers blood pressure. Angiotensin II Receptor Blockers (ARBs) As mentioned above, angiotensin is a chemical that narrows the arteries. ARBs block the effect the chemical has on the blood vessels, preventing constriction and allowing them to remain open, thus reducing blood pressure. Calcium Channel Blockers When calcium enters the smooth muscle cells of the heart, it causes stronger, harder contractions. Calcium channel blockers prevent calcium from entering the heart cells resulting in less forceful contractions and reduced heart rate. Calcium channel blockers also relax and open up narrowed blood vessels which, together with the lower heart rate, helps to lower blood pressure. Beta Blockers Beta-blockers cause the heart to beat more slowly and with less force. This lessens the heart's output of blood and widens blood vessels, both of which can lower blood pressure. Beta blockers are often most effective when combined with other blood pressure medications. The five medication types listed above are the most common but there are many other types of medications that may be recommended for you. And, some people will require more than one medication to effectively manage their blood pressure. Your doctor will work with you to find the right drug or combination of drugs and the right dosage to get your hypertension under control.Early Detection Is Key
Although more common in older people, hypertension can occur in anyone – young, old, fit, not-so-fit, thin and overweight. That is why it’s important to have your blood pressure checked regularly, ideally at your annual physical exam with a primary care provider. “The key is early identification,” says Ian Neeland, MD,Director of Cardiovascular Disease Prevention at UH Harrington Heart & Vascular Institute. “Once hypertension has been diagnosed, we work with each patient to find the right combination of lifestyle modifications and medications to reach their blood pressure goal. With the right treatment, complications of hypertension can be prevented, and, in some cases, damage can be reversed,” he adds. “The main takeaway is that good blood pressure helps people live longer, healthier lives.”Ultra Cardio+
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